Our Mission
The standard TB treatment, though effective, requires patients to take a daily combination of drugs for six months. This long duration often leads to incomplete treatment, resulting in relapse, resistance, and continued spread of the disease.
At World Without Tuberculosis (WWTB), our mission is to change that.
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We work to reduce treatment time using drugs already in use — but at more effective doses and combinations — through carefully conducted clinical trials. While new TB drug development can take 20 years+ and require over $1 billion in funding, our model reduces time and cost by safely rethinking how existing treatments are used.
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How We Work
We believe in a deeply collaborative model that blends scientific rigour with real-world constraints.
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We set honest, achievable goals, backed by strong laboratory and human trial evidence.
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We foster open knowledge-sharing among global researchers.
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We focus on realistic, affordable approaches for high-burden settings.​
Our Focus Areas
01
Clinical
Trials
Since the discovery of streptomycin in 1944, clinical trials have driven every major breakthrough in TB treatment. WWTB supports trials designed to:
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Reduce treatment duration from 6 to 2 months
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Improve patient adherence
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Lower health system strain
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Use existing drugs, tested at optimised doses
We currently support studies such as those led by the INTERTB Consortium at City St George’s, University of London. Our research focuses especially on higher-dose rifampicin, which has shown promising safety and efficacy in early studies.
02
Built International Partnerships
We have collaborated with healthcare professionals and researchers globally, including in high disease areas across Africa, Asia, and Eastern Europe to strengthen TB care and research capacity.
03
Equipment
Supply
We provide labs and research centres with the tools they need to run high-quality studies — from lab equipment to data management systems.​​
04
Training
Our support includes training for clinical and lab staff in:
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Safe equipment use
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Digital data management
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Research best practices​
05
Workshops
We facilitate regional and international workshops on:
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Protocol design
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Trial management
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Good Clinical Practice (GCP) guidelines
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Cross-site collaboration